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For example, in alveolar macrophages, GLP-1 receptor agonism suppressed activation of the NLRP3 inflammasome and reduced production of IL-1 [65], an effect in part mediated by the disruption of histone lactylation, a recognised regulator of pro-fibrotic gene expression [65]

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The GLP-1 RA Weight Loss Drug Lawsuit: A Must-Know Update for Mass Tort Lawyers GLP-1 RA, a weight loss drug initially intended for managing type 2 diabetes, has come under intense legal scrutiny due to reports of severe side effects

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